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Diffusion tensor imaging detects Wallerian degeneration of the corticospinal tract early after cerebral infarction

Ruiman Xie Min Fang Linjiang Zhou Shanghua Fan Jianying Liu Hongbo Quan Man Luo Dongying Qiu

中国神经再生研究(英文版)2012,Vol.7Issue(12):900-905,6.
中国神经再生研究(英文版)2012,Vol.7Issue(12):900-905,6.DOI:10.3969/j.issn.1673-5374.2012.12.004

Diffusion tensor imaging detects Wallerian degeneration of the corticospinal tract early after cerebral infarction

Diffusion tensor imaging detects Wallerian degeneration of the corticospinal tract early after cerebral infarction

Ruiman Xie 1Min Fang 1Linjiang Zhou 2Shanghua Fan 1Jianying Liu 1Hongbo Quan 1Man Luo 1Dongying Qiu1

作者信息

  • 1. Department of Neurology and Gerontology, Zhongshan Hospital, Fudan University, Shanghai 200032, China
  • 2. Department of Radiology, Huashan Hospital, Fudan University, Shanghai 200040, China
  • 折叠

摘要

Abstract

To investigate the feasibility and time window of early detection of Wallerian degeneration in the corticospinal tract after middle cerebral artery infarction, 23 patients were assessed using magnetic resonance diffusion tensor imaging at 3.0T within 14 days after the infarction. The fractional anisotropy values of the affected corticospinal tract began to decrease at 3 days after onset and decreased in all cases at 7 days. The diffusion coefficient remained unchanged. Experimental findings indicate that diffusion tensor imaging can detect the changes associated with Wallerian degeneration of the corticospinal tract as early as 3 days after cerebral infarction.

关键词

corticospinal tracts/Wallerian degeneration/fractional anisotropy/diffusion tensor imaging/neuroimaging/neural regeneration

Key words

corticospinal tracts/Wallerian degeneration/fractional anisotropy/diffusion tensor imaging/neuroimaging/neural regeneration

引用本文复制引用

Ruiman Xie,Min Fang,Linjiang Zhou,Shanghua Fan,Jianying Liu,Hongbo Quan,Man Luo,Dongying Qiu..Diffusion tensor imaging detects Wallerian degeneration of the corticospinal tract early after cerebral infarction[J].中国神经再生研究(英文版),2012,7(12):900-905,6.

基金项目

This study was supported by the National Stroke Rehabilitation Research Foundation of the Ministry of Health,China,No.01BA703B18b and the Young and Middle-Aged Clinical Scientists Research Foundation of Shanghai Government,No.01YZK. ()

中国神经再生研究(英文版)

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