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β-羟丁酸对中枢神经系统的作用及机制研究进展

文静 付守鹏 柳巨雄

中国畜牧兽医2012,Vol.39Issue(2):106-110,5.
中国畜牧兽医2012,Vol.39Issue(2):106-110,5.

β-羟丁酸对中枢神经系统的作用及机制研究进展

Research Progress on the Roles of β-hydroxybutyric Acid Played in Central Nervous System and Mechanism

文静 1付守鹏 1柳巨雄1

作者信息

  • 1. 吉林大学畜牧兽医学院,吉林长春130062
  • 折叠

摘要

Abstract

β-hydroxybutyric acid(BHBA) is an important component of ketone bodies in blood. BHBA is utilized as an energy source by the brain particularly in suckling newborns and under starving conditions. Speculate as further signal material adjust energy central and as a biological oxidation substrate adjust feeding. Because BHBA has nerve protective effect, it may be an effective way of treatment of neuron degenerative disease. Therefore, the purpose of this review is to summarize the known central effects of BHBA and to point out the possible cellular pathways triggered in response to BHBA.

关键词

β-羟丁酸/中枢神经系统/神经保护/信号通路

Key words

β-hydroxybutyric acid/central nervous system/neuroprotection/signal pathway

分类

农业科技

引用本文复制引用

文静,付守鹏,柳巨雄..β-羟丁酸对中枢神经系统的作用及机制研究进展[J].中国畜牧兽医,2012,39(2):106-110,5.

基金项目

国家重点基础研究发展计划(973计划)(2011CB100805). (973计划)

中国畜牧兽医

OA北大核心CSTPCD

1671-7236

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