中国畜牧兽医2012，Vol.39Issue(2)：114-117,4.
湖羊瘦素基因内含子2多态性及其与体重性状的相关性分析
The Polymorphism of leptin Gene Intron 2 in Hu Sheep and its Influence on the Body Weight Traits
摘要
Abstract
Sequencing and PCR-RFLP were applied to detect single nucleotide polymorphism (SNP) in intron 2 of leptin gene in 85 Hu sheep. Two SNPs of A99G and C150T were found. The dominant genotypes in the two loci were both wild genotype, genotype frequencies were 0. 7882 and 0. 8000, respectively. Mutation genotype was not found in the both loci. Chi-square test showed that the population was at Hardy-Weinberg equilibrium(P>0. 05). Association analysis between the SNPs and body weight traits showed that the genotypes on the two loci had no significant influence on birth weight, 3-month weight and 6-month weight (P>0. 05).关键词
湖羊/leptin基因/SNP/体重性状/相关分析Key words
Hu sheep/leptin gene/SNP/body weight traits/association analysis分类
生物科学引用本文复制引用
吴丽丽,赵晓枫,陈哲,张立凡,蒋晓玲,吕尊周,徐宁迎..湖羊瘦素基因内含子2多态性及其与体重性状的相关性分析[J].中国畜牧兽医,2012,39(2):114-117,4.基金项目
浙江省科技厅重大专项(2007C12057). （2007C12057）
