中国畜牧兽医2012，Vol.39Issue(2)：121-124,4.
蒙古羊GDF11基因启动子区克隆及序列分析
Cloning and Sequence Analysis of the Promoter Region of Mongolian Sheep GDF11 Gene
摘要
Abstract
In order to analysis the relationship between growth differentiate factor 11 (GDF11) and the traits of more vertebras of Mongolian sheep, the gene promoter region was cloned firstly and analysised by the bioinformatics software. The results showed that the GDF11 gene promoter region length was 512 bp and bases proportion were A 10. 55%, G 16. 80%, T 31. 84% , C 40. 82% . The proportion of G+C was 57. 62%. The results of bioinformatics analysis showed no CpG island and TATA box or CAAT box found in the Mongolian sheep GDF11 gene promoter region, but existed one transcription initiation site, 5 transcription factors: HSF2, HSF2, GATA-1, AML-1a, MZF1, and 5 motifs: EGF_1, CTCK_1, ANAPHYLATOX-IN_1, VWFC_1, DEFENSIN. The research provided theoretical basis for the Mongolian sheep vertebra regulation mechanism by GDF11 gene.关键词
蒙古羊/GDF11基因/启动子/转录因子Key words
Mongolian sheep/ GDF11 gene/ promoter/ transcription factor分类
生物科学引用本文复制引用
何小龙,李蓓,刘永斌,王峰,田春英,荣威恒..蒙古羊GDF11基因启动子区克隆及序列分析[J].中国畜牧兽医,2012,39(2):121-124,4.基金项目
内蒙古自治区农牧业科学院青年创新基金和国家肉羊产业技术体系(CARS-39). （CARS-39）
