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奶牛白细胞黏附缺陷症(BLAD)检测方法的研究进展

周莉 贾广乐 张映 韩雪清 林祥梅

中国畜牧兽医2012,Vol.39Issue(2):137-140,4.
中国畜牧兽医2012,Vol.39Issue(2):137-140,4.

奶牛白细胞黏附缺陷症(BLAD)检测方法的研究进展

Progress on the Study of the Test Methods for Bovine Leukocyte Adhesion Deficiency(BLAD)

周莉 1贾广乐 2张映 1韩雪清 2林祥梅1

作者信息

  • 1. 中国检验检疫科学研究院,北京100121
  • 2. 山西农业大学动物科技学院,山西太谷030801
  • 折叠

摘要

Abstract

Bovine leukocyte adhesion deficiency (BLAD) is a newly discovered autosomal recessive genetic disease in recent years caused by A→G mutation in the CD18 gene. The disease is characterized by greatly reduced expression of the hetero di-meric β2 integrin adhesion molecules on leukocytes resulting in multiple defects in leukocyte function and significant deficits on performance traits in Holstein cattle. The main features of sick cattle is immunity reduction, susceptibility to diseases and affecting production performance. This review focus on the progress of test methods of BLAD.

关键词

白细胞黏附缺陷症/检测方法/研究进展

Key words

bovine leukocyte adhesion deficiency/test methods/progress on the study

分类

农业科技

引用本文复制引用

周莉,贾广乐,张映,韩雪清,林祥梅..奶牛白细胞黏附缺陷症(BLAD)检测方法的研究进展[J].中国畜牧兽医,2012,39(2):137-140,4.

基金项目

五种牛隐性遗传缺陷病及布病检疫技术和标准研究(20120122) (20120122)

质检总局科研项目"奶牛两种隐性遗传疾病分子筛查方法的建立"(20111K021). (20111K021)

中国畜牧兽医

OA北大核心CSTPCD

1671-7236

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