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冷应激条件下猪脂肪组织中脂联素及其受体mRNA水平的表达变化

付守鹏 柳巨雄 王玮 郭斌 胡仲明 任保彦 刘颖 李苏楠 李洋 王茂鹏 杨占清 魏利斌 李志强

中国畜牧兽医2012,Vol.39Issue(3):28-32,5.
中国畜牧兽医2012,Vol.39Issue(3):28-32,5.

冷应激条件下猪脂肪组织中脂联素及其受体mRNA水平的表达变化

Adiponectin and its Receptors mRNA Levels in Swine Adipose Tissue in the Condition of Cold Stress

付守鹏 1柳巨雄 1王玮 1郭斌 1胡仲明 2任保彦 1刘颖 1李苏楠 1李洋 1王茂鹏 1杨占清 1魏利斌 1李志强1

作者信息

  • 1. 吉林大学畜牧兽医学院,吉林长春 130062
  • 2. 军事医学科学院实验动物中心,北京100000
  • 折叠

摘要

Abstract

The adipose tissue samples in the neck, pars dorsalis and viscera mesenteria of pig under the temperature of -15~ - 10 °C , -10~ -5 °C , - 5~0 °C , 15 -18 °C were collected for sthdying the expression of adiponectin and adiponectin receptors mRNA by Real-time fluorescent quantification reverse transcriptase PCR to explore the effects of cold stress on lipome-tabolism. The results showed that the expression of adiponectin mRNA in the neck, pars dorsalis and viscera mesenteria gradually decreased with the increasing cold stimulus and the differences were significant (P<0. 05). The levels of AdipoR 1 and AdipoR 2 mRNA in viscera mesenteria firstly increased and then declined (P<C0. 01). The expression of AdipoR 2 mRNA in pars dorsalis gradually decreased and then returned the normal level; AdipoR 1 mRNA of the different groups had no obvious difference. AdipoR 2 mRNA in the neck went up gradually and declined to the normal level(P<0. 01) ; AdipoR 1 mRNA firstly increased then down-regulated to normal level and went up again(P<0. 01). It was concluded that adiponectin and AdipoR are associated with the process of cold stress, which may play important role on redistribution of adipose tissue under animal cold stress.

关键词

冷应激/脂联素/脂联素受体1/脂联素受体2

Key words

cold stress/ Adiponectin/ Adiponectin receptor 1 (AdipoR 1) /Adiponectin receptor 2 (AdipoR 2)

分类

生物科学

引用本文复制引用

付守鹏,柳巨雄,王玮,郭斌,胡仲明,任保彦,刘颖,李苏楠,李洋,王茂鹏,杨占清,魏利斌,李志强..冷应激条件下猪脂肪组织中脂联素及其受体mRNA水平的表达变化[J].中国畜牧兽医,2012,39(3):28-32,5.

基金项目

国家自然基金(30972155). (30972155)

中国畜牧兽医

OA北大核心CSTPCD

1671-7236

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