中国畜牧兽医2012，Vol.39Issue(3)：65-70,6.
甘露糖结合凝集素相关的丝氨酸蛋白酶2研究进展
Progress of Mannose-binding Lectin-associated Serine Protease 2
摘要
Abstract
MBL-associated serine protease (MASP) and mannan-binding lectin (MBL) are key factors of the lectin pathway of complement activation and play an important role in the defense. MBL or ficolin can form complexes with sugars presented on pathogens through its carbohydrate recognition domain (CRD) and its collagen-like region (CLR) can recognize and binding to MASP. MBL can activity the zymogens of MASP which is a key enzyme and activate the complement cascade through lectin pathway.关键词
丝氨酸蛋白酶/凝集素途径/分子结构/功能Key words
MASP/ the lectin pathway/ molecular structure/ function分类
生物科学引用本文复制引用
王新菊,鞠志花,王长法,李国荣..甘露糖结合凝集素相关的丝氨酸蛋白酶2研究进展[J].中国畜牧兽医,2012,39(3):65-70,6.基金项目
国家“科技支撑计划”项目(编号:2011BAD19BO4) （编号:2011BAD19BO4）
农业部转基因重大专项(2011 ZX08007-004) （2011 ZX08007-004）
山东省良种工程项目(2010LZ015-06). （2010LZ015-06）
