中国畜牧兽医2012，Vol.39Issue(3)：85-88,4.
miRNA对干细胞重编程的影响
The Influence of miRNA to Stem Cell Reprogramming
摘要
Abstract
The varied roles played by miRNA in the maintenance of embryonic stem (ES) cell self-renewal and pluripoten-cy. Several recent studies that have begun to probe the roles of miRNAs during the reprogramming of somatic cells into induced pluripotent stem (IPS) cells. Subsequently, the function of numerous miRNAs has been shown to control the fate of ES cells and to directly influence critical gene regulatory networks controlled by pluripotency factors Sox2, Oct4, and Nanog. miRNAs are likely to influence the process of reprogramming. In addition, we posit that more than a dozen additional miRNAs are excellent candidates for influencing the generation of IPS cells.关键词
miRNA/重编程/胚胎干细胞/诱导性多能干细胞Key words
miRNA/reprogramming/ES cell/IPS cell分类
生物科学引用本文复制引用
包阿东,苏志芳,陆涛峰,马惠茹,汪长寿..miRNA对干细胞重编程的影响[J].中国畜牧兽医,2012,39(3):85-88,4.基金项目
国家科技支撑项目(2006BAD13B08 （）
2008BADB2B01). （）
