中国畜牧兽医2012，Vol.39Issue(3)：134-136,3.
病毒感染与细胞核转录因子-κB信号转导的相互作用关系
Interaction between Virus Infection and NF-kappaB Signal Transduction
摘要
Abstract
Since we found NF-kappaB, it has been studied widely about its molecular biology characteristics,function mechanism and the relationships with diseases. Recently many studies reveal that the NF-kappaB plays an important role in the process of virus infection and disease. The translocation of NF-kappaB from the cytoplasm to the nucleus can be induced when virus infect eukaryotic cells,consequently or inducing transcription of some inflammatory gene to produce a lot of inflammatory factors,or blocking apoptosis and prolonging survival of the host cell to gain time for replication and increase viral progeny production, or promoting the expression of oncogene to make cells cancerization.and so on. Once virus infection, body properties will be changed through NF-kappaB signal transduction and diseases will appear soon. Many fators, which has been found at present,such as stress stimulator,LPS,virus,oxygen free radical and so on,are all able to activate the NF-kappaB and then affect the body's metabolism through NF-kappaB signal pathway. In this paper,the interaction between virus infection and NF-kappaB signal transduction is reviewed.关键词
病毒感染/核转录因子-κB/信号转导Key words
virus infection/nuclear transcription factor-icB/signal transduction分类
农业科技引用本文复制引用
黄慧,严玉霖,高洪,高利波,赵汝,陈玲,蒋欢,陈冈..病毒感染与细胞核转录因子-κB信号转导的相互作用关系[J].中国畜牧兽医,2012,39(3):134-136,3.基金项目
云南省高校科技创新团队支持计划资助项目(云教科[2011]4号) （云教科[2011]4号）
云南省现代农业生猪产业技术体系建设(云财农[2010]119号) （云财农[2010]119号）
云南省高端科技人才引进计划项目(2009CI125). （2009CI125）
