中国药房2012,Vol.23Issue(10):881-883,3.DOI:10.6039/j.issn.1001-0408.2012.10.07
某“三甲”医院利奈唑胺注射剂临床应用合理性评价
Rationality Evaluation of Clinical Application of Linezolid Injection in a Class Three Grade A Hospital
包雯 1姜玲 2孙言才 1史天陆 2杨昭毅 2魏伟2
作者信息
- 1. 安徽医科大学临床药理研究所/抗炎免疫药理学省部共建教育部重点实验室,合肥230032
- 2. 安徽医科大学附属省立医院药剂科,合肥230001
- 折叠
摘要
Abstract
OBJECTIVE: To investigate the rationality of clinical application of Linezolid injection in a Class Three Grade A hospital. METHODS:We selected the medical records of inpatients treated with Linezolid injection in the hospital from 2009 -2010. The application of Linezolid injection was analyzed, referring to package inserts and relevant guidelines for diagnosis and treatment. RESULTS: Of the 163 patients, there were 10 patients aged below 11, accounting for 6.13%, 153 aged 12 or above ac-counted for 93.87% ; there were 106 cases of rational drug use (65.03% ), 57 unreasonable cases (34.97% ); 112 patients were cured(68.71%), 25 were effected(15.34%),9 were improved(5.52%),while 17 were invalid( 10.43%). 18 patients suffered from thrombocytopenia after medication(11.04%). CONCLUSION: Linezolid injection is effective in the treatment on Gram-positive bac-teria infections. Research shows that it has high rate of adverse effect on platelet, which should be confirmed in future practice.关键词
利奈唑胺注射剂/合理用药/评价/血小板减少Key words
Linezolid injection/ Rational drug use/ Evaluation/ Thrombocytopenia分类
医药卫生引用本文复制引用
包雯,姜玲,孙言才,史天陆,杨昭毅,魏伟..某“三甲”医院利奈唑胺注射剂临床应用合理性评价[J].中国药房,2012,23(10):881-883,3.