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某“三甲”医院利奈唑胺注射剂临床应用合理性评价

包雯 姜玲 孙言才 史天陆 杨昭毅 魏伟

中国药房2012,Vol.23Issue(10):881-883,3.
中国药房2012,Vol.23Issue(10):881-883,3.DOI:10.6039/j.issn.1001-0408.2012.10.07

某“三甲”医院利奈唑胺注射剂临床应用合理性评价

Rationality Evaluation of Clinical Application of Linezolid Injection in a Class Three Grade A Hospital

包雯 1姜玲 2孙言才 1史天陆 2杨昭毅 2魏伟2

作者信息

  • 1. 安徽医科大学临床药理研究所/抗炎免疫药理学省部共建教育部重点实验室,合肥230032
  • 2. 安徽医科大学附属省立医院药剂科,合肥230001
  • 折叠

摘要

Abstract

OBJECTIVE: To investigate the rationality of clinical application of Linezolid injection in a Class Three Grade A hospital. METHODS:We selected the medical records of inpatients treated with Linezolid injection in the hospital from 2009 -2010. The application of Linezolid injection was analyzed, referring to package inserts and relevant guidelines for diagnosis and treatment. RESULTS: Of the 163 patients, there were 10 patients aged below 11, accounting for 6.13%, 153 aged 12 or above ac-counted for 93.87% ; there were 106 cases of rational drug use (65.03% ), 57 unreasonable cases (34.97% ); 112 patients were cured(68.71%), 25 were effected(15.34%),9 were improved(5.52%),while 17 were invalid( 10.43%). 18 patients suffered from thrombocytopenia after medication(11.04%). CONCLUSION: Linezolid injection is effective in the treatment on Gram-positive bac-teria infections. Research shows that it has high rate of adverse effect on platelet, which should be confirmed in future practice.

关键词

利奈唑胺注射剂/合理用药/评价/血小板减少

Key words

Linezolid injection/ Rational drug use/ Evaluation/ Thrombocytopenia

分类

医药卫生

引用本文复制引用

包雯,姜玲,孙言才,史天陆,杨昭毅,魏伟..某“三甲”医院利奈唑胺注射剂临床应用合理性评价[J].中国药房,2012,23(10):881-883,3.

中国药房

OACSCDCSTPCD

1001-0408

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