中国医学科学院学报2012，Vol.34Issue(1)：51-57,7.DOI:10.3881/j.issn.1000-503X.2012.01.010
兔肝脏3.0T磁共振弥散加权成像的实验研究
An Experimental Study on Rabbit Liver by 3.0 Tesla Magnetic Resonance Diffusion-weighted Imaging
董天明 1孙希杰 2徐贤 1戴静 3郑伟 4安宁豫 1王晓卿5
作者信息
- 1. 中国人民解放军总医院放射科
- 2. 中国人民解放军海军总医院放射科,北京100048
- 3. 中国人民解放军总医院动物实验中心,北京100853
- 4. 中国人民解放军261医院放射科,北京100094
- 5. 595820部队卫生队,北京102207
- 折叠
摘要
Abstract
Objective To explore the methodology as well as the features, quantificational index, and reference standard of 3. 0 Tesla magnetic resonance ( MR) diffusion-weighted imaging ( DWI) on the normal rabbit's liver. Methods Twenty New Zealand white rabbits were enrolled and DWI was performed after anesthetics with multi-b values at 3. OT MR scanner. Apparent diffusion coefficient ( ADC) values as well as the difference between maximum and minimum ADC values, signal strength ( SH), noise signal (SD), signal to noise ratio (SNR) , and quality index ( QI) were recorded and analyzed. Results With b value increased, the ADC values decreased accordingly (P <0. 001). The difference between maximum and minimum ADC values with b = 1000 s/mm2 was the least (good stability) , b = 600 s/mm2 was the second least, and b = 300 s/mm2 was greatest (bad stability). The SH decreased at the same time ( P < 0. 001), but the difference among DWI with b=600, 800, and 1000 s/mm2 was not statistically significant (P>0. 05). The SD decreased at the same time (P <0. 001) , but the difference between DWI with b = 800 s/mm2 and b = 1000 s/mm2 was not statistically significant (P > 0. 05 ). The SNR decreased at the same time (P < 0. 001), but there were no significant differences between DWI with b =600 s/mm2 and b =800 s/mm2 or b =600 s/mm2 and b = 1000 s/mm2 (P > 0. 05). The SNR of DWI with b = 800 s/mm2 and b = 1000 s/mm2 was lower. The QI decreased at the same time (P<0. 001) , but the difference between DWI with b =800 s/mm2 and b = 1000 s/mm2 was not statistically significant (P >0. 05). Conclusion When 3. 0T MR DWI is applied for rabbit liver, it is better to use b = 600 s/mm2 for reducing scanning time and assuring better diffusion weights, quantity of images, and stability of ADC measurement.关键词
肝脏/磁共振/弥散加权成像/动物实验Key words
liver/magnetic resonance imaging/diffusion-weighted imaging/animal experiment分类
医药卫生引用本文复制引用
董天明,孙希杰,徐贤,戴静,郑伟,安宁豫,王晓卿..兔肝脏3.0T磁共振弥散加权成像的实验研究[J].中国医学科学院学报,2012,34(1):51-57,7.
