中国药业2012,Vol.21Issue(7):15-16,2.
不同溶出介质的多条溶出曲线评价盐酸普萘洛尔片内在质量
Evaluation of Quality of Propranolol Hydrochloride Tablets by Dissolution Curves in Different Mediums
摘要
Abstract
Objective To detect the dissolution of propranolol hydrochloride tablets from different pharmaceutical factories in 4 different mediums and evaluate the quality by dissolution curves. Methods The dissolution test was carried out with paddle - rotating method. To analyse and compare the results by the dissolution curves in different mediums. Results and Conclusion There was significant difference in dissolution parameters and the quality among the propranolol hydrochloride tablets preparations from different manufactories.关键词
盐酸普萘洛尔片/溶出度/溶出曲线/紫外分光光度法Key words
Propranolol Hydrochloride Tablets/dissolution/Weibull Equation/UV - spectrophotometry分类
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刘海涛,王俊秋,余立..不同溶出介质的多条溶出曲线评价盐酸普萘洛尔片内在质量[J].中国药业,2012,21(7):15-16,2.