中国药业2012，Vol.21Issue(7)：41-42,2.
甘精胰岛素联合格列美脲治疗2型糖尿病80例
Insulin Glargine Combined Glimepiride for Treating 80 Cases of Type 2 Diabetes Mellitus
傅海东1
作者信息
- 1. 浙江省宁波市海曙区南门社区卫生服务中心,浙江宁波,315010
- 折叠
摘要
Abstract
Objective To explore the efficacy and safety of insulin glargine combined glimepiride in the treatment of type II diabetes meUitus (T2DM). Methods Eighty cases of T2DM with fasting blood glucose (FBG) ≥ 10 mmol/L in our hospital from October 2008 to September 2011 were treated with insulin glargine by subcutaneous injection before going to bed and oral glimepiride for 12 weeks. The dosage of insulin was adjusted according to FBG levels, the goals of treatment was 5. 5 mmol/L < FBG < 7 mmol/L. The changes of FBG, postprandial 2 hFBG, glycated hemoglobin (HbAlc), C - peptide, hypoglycemia and body mass index (BMI) before and after treatment were observed. Results Compared with before treatment, FBG, postprandial 2hFBG and HbAlc were significantly decreased after treatment (P< 0.05), and C-peptide level was significantly improved( P < 0. 05). 5 cases had hypoglycemia with the incidence rate of 6. 25%, which was significantly lower than that before treatment ( P < 0. 05). BMI had no significant change (P> 0. 05). Conclusion Insulin glargine combined glimepiride is effective for treating T2DM with the low rate of hypoglycemia and good safety, which is the ideal treatment scheme of T2DM.关键词
甘精胰岛素/格列美脲/2型糖尿病Key words
insulin glargine/glimepiride/type Ⅱ diabetes mellitus分类
医药卫生引用本文复制引用
傅海东..甘精胰岛素联合格列美脲治疗2型糖尿病80例[J].中国药业,2012,21(7):41-42,2.
