中国药业2012，Vol.21Issue(7)：52-53,2.
卡培他滨联合奥沙利铂治疗恶性结、直肠肿瘤50例
Capecitabine and Oxaliplatin for Treating Malignant Colorectal Tumor in 50 Cases
郭东升 1董柏年1
作者信息
- 1. 浙江省宁波市第六医院普外科,浙江,宁波315040
- 折叠
摘要
Abstract
Objective To explore the efficacy and safety of capecitabine and oxaliplatin in the treatment of malignant colorectal tumor. Methods Ninety-six patients with malignant colorectal tumors were randomly divided into two groups. The control group (ra=46) was given oxaliplatin, while the experimental group (n = 50) were treated by capecitabine and oxaliplatin. The clinical efficacy and adverse reactions after treatment were observed and compared between the two groups. Results The total effective and disease control rate in the experimental group were 52. 00% and 84. 00% respectively, which were 26. 09% and 56. 52% in the control group, the former was significantly higher than the latter( P<0. 05). The incidence of adverse reactions had no statistical difference between the two groups(P> 0.05). Conclusion Capecitabine plus oxaliplatin in the treatment of malignant colorectal tumor has definite efficacy and less adverse reactions, which is suitable to be popularized in clinical practice.关键词
结、直肠肿瘤/化学治疗/卡培他滨/奥沙利铂Key words
colorectal cancer/chemotherapy/capecitabine/oxaliplatin分类
医药卫生引用本文复制引用
郭东升,董柏年..卡培他滨联合奥沙利铂治疗恶性结、直肠肿瘤50例[J].中国药业,2012,21(7):52-53,2.
