中国药业2012，Vol.21Issue(7)：57-58,2.
紫杉醇辅助化学治疗妇科恶性肿瘤52例
Paclitaxel Adjuvant Chemotherapy for Treating 52 Cases of Gynecologic Malignancies
马美芬1
作者信息
- 1. 浙江省临安市人民医院妇产科,浙江杭州,311300
- 折叠
摘要
Abstract
Objective To study the clinical efficacy of paclitaxel adjuvant chemotherapy in the treatment of ovarian cancer. Methods A hundred and four cases of ovarian cancer in our hospital from July 2006 to June 2008 were randomly divided into two groups, 52 cases in each group. The treatment group was treated with the paclitaxel adjuvant chemotherapy, while the control group received ifosfamide adjuvant chemotherapy treatment. The clinical efficacy and toxicity of chemotherapy were observed in the two groups. Results The effective rate was 34.62% in the control group and 50.00% in treatment group, showing statistical difference between the two groups(P< 0.05). The overall survival period was 1.8 years in the control group and 2.9 years in the treatment group with statistical difference between them ( P < 0. 05). The main toxic and adverse reactions of chemotherapy were hematologic toxicity, alopecia, rash, vomiting, allergies and so on. Conclusion The paclitaxel adjuvant chemotherapy for treating ovarian cancer has good effects, the toxicity is relatively mild and tolerable, which can be popularized in clinical practice.关键词
紫杉醇/辅助化学治疗/异环磷酰胺/卵巢癌Key words
paclitaxel/adjuvant chemotherapy/ifosfamide/ovarian cancer分类
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马美芬..紫杉醇辅助化学治疗妇科恶性肿瘤52例[J].中国药业,2012,21(7):57-58,2.
