中国中西医结合外科杂志2012，Vol.18Issue(2)：110-113,4.DOI:10.3969/j.issn.1007-6948.2012.02.002
早期胃癌淋巴结转移潜在危险因素分析
Potential Risk Factors of Lymph Node Metastasis with Early Gastric Cancer
摘要
Abstract
Objective To analyze the potential risk factors of lymph node metastasis with early gastric cancer (EGC) and to provide references for the clearance of lymph nodes(Dl or D2). Methods Three hundred and thirty-six patients with EGC removed surgically from Mar 1995 to Jun 2010 were analyzed retrospectively, the clinicopathologic features and lymph node metastasis were analyzed by univariate analysis and multivariate analysis. Results Univariate analysis revealed correlations between lymph node metastasis and various factors ranging from patient's gender(P=0.010), patient's age(P=0.013), location of tumor (P=0.042), presence of an ulcer (P=0.001), depth of invasion (P <0.000l) and presence of lymphatic thrombi involvement (P <0.000l). However, in multivariate analysis, presence of an ulcer (P=0.012), invasion to the submucosal (P=0.008),and lymphatic involvement(P=0.00l) were found to be independent risk factors. While in patients with intramucosal EGC, the tumor size (P=0.007) and location of tumor (P=0.0l0) were risk factors, tumor diameter> 20 mm(P= 0.041) was the only independent risk factor. Conclusions In case of the Presence of an ulcer, invasion into the submucosa and vascular invasion in patients with early gastric cancer, lymph node dissection should be con-sidered(D2).Also in those with intramucosal cancer and the tumor diameter greater than 20 mm should be considered lymph node dissection(D2) should be considered.关键词
早期胃癌/临床病理特征/淋巴结转移/危险因素Key words
Early gastric cancer/Clinicopathological characteristics/Lymph node metastasis/Risk factors分类
医药卫生引用本文复制引用
杨磊磊,戴岳楚,董米连,杨秀英,叶甫波,廖伟,梅统..早期胃癌淋巴结转移潜在危险因素分析[J].中国中西医结合外科杂志,2012,18(2):110-113,4.基金项目
浙江省医学会临床科研基金项目(2009ZYC50) （2009ZYC50）
台州市科技计划项目(2010-26-48) （2010-26-48）
