类风湿关节炎患者血清白细胞介素-33水平与疾病进程的相关性OACSTPCD
Serum Level of Interleukin-33 in Patients with Rheumatoid Arthritis and Its Clinical Significance
目的 通过检测类风湿关节炎(RA)患者血清中白细胞介素(IL)-33水平,分析血清IL-33水平与RA的临床及实验室指标之间的相关性,验证IL-33参与RA的发病过程,探讨IL-33对于RA的临床意义.方法 采用ELISA方法测定70例RA患者和30例健康对照者血清IL-33水平.结果 RA组血清IL-33水平为(231±335)pg/ml,高于健康对照组(6±23)pg/ml,P<0.01.高疾病活动度组血清IL-33水平为(351±…查看全部>>
To test the serum level of interleukin( IL )-33 in patients with rheumatoid arthritis( RA ) and analyze its correlation with both clinical and laboratory parameters. Methods Seventy patients with RA were selected, and 30 healthy controls were selected as controls. The serum IL-33 levels of the two groups were detected by enzyme-linked immunosorbent assay( ELISA ). Results The serum level of IL-33 in RA patients [ ( 231 ±335 )pg/ml ] was higher than that of t…查看全部>>
薛红霞;刘冬梅;崔华东;付文轶;杨丽丽;赵丽娟;张宁
中国医科大学,附属盛京医院风湿免疫科,沈阳,110000中国医科大学,附属盛京医院风湿免疫科,沈阳,110000中国医科大学,附属盛京医院风湿免疫科,沈阳,110000中国医科大学,附属盛京医院风湿免疫科,沈阳,110000中国医科大学,附属盛京医院风湿免疫科,沈阳,110000中国医科大学附属第一医院风湿免疫科,沈阳,110000中国医科大学,附属盛京医院风湿免疫科,沈阳,110000
医药卫生
类风湿关节炎白细胞介素-33类风湿因子抗环瓜氨酸肽抗体
rheumatoid arthritisinterleukin-33rheumatoid factoranti-cyclic citrullinated peptide antibody
《中华临床免疫和变态反应杂志》 2012 (1)
PADI4、PTPN22基因多态性与类风湿关节炎相关性的研究
6-9,4
国家自然科学基金(81072450)
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