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重型颅脑损伤后高钠血症与预后关系分析

滕灵方 邵波

浙江医学2012,Vol.34Issue(5):353-355,3.
浙江医学2012,Vol.34Issue(5):353-355,3.

重型颅脑损伤后高钠血症与预后关系分析

Relationship between hypernatremia and prognosis of patients with severe traumatic brain injury

滕灵方 1邵波1

作者信息

  • 1. 317500,温岭市第一人民医院神经外科
  • 折叠

摘要

Abstract

Objective To investigate the relation between hypernatremia and the prognosis of patients with severe trau-matic brain injury.Methods MethodsThe clinical data of 186 patients with severe traumatic brain injury admitted from Jan 2009 to Dec2010 were retrospectively analyzed. The serum concentration of sodium was measured twice a day, and >150mmol/L was defined as hypernatremia. Patients with operational indications received surgical treatment, others underwent conservative managements, including dehydration, infection prevention, hemostasis, and nutrition support.results ResultsTwenty five patients died in 47 patients with hypernatremia (53.2%), while 31 patients died in 139 patients without hypernatremia(22.3%)(P<0.05). There were 33 most severe brain injured cases(GCS 3-5 Jin 47 hypernatremic patients(70.2%),compared to 52 most severe cases in 139 non-hypernatremic patients (37.4%)(P<0.05). Hypernatremia is a severe complication of traumatic brain injury, which is associated with poor prognosis and high mortality of patients.

关键词

颅脑损伤/高钠血症/预后

Key words

Traumatic brain injury/Hypernatremia/Prognosis

引用本文复制引用

滕灵方,邵波..重型颅脑损伤后高钠血症与预后关系分析[J].浙江医学,2012,34(5):353-355,3.

基金项目

温岭市科学技术局科技计划项目(2009WLCB0074) (2009WLCB0074)

浙江医学

OACSTPCD

1006-2785

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