浙江医学2012，Vol.34Issue(5)：356-358,363,4.
小儿支原体肺炎临床特征及大环内酯类抗生素疗效分析
Clinical characteristics and macrolide antibiotics treatment of mycoplasma pneumonia in children
摘要
Abstract
Objective To review the clinical characteristics and antibiotic treatment of mycoplasma pneumonia (MP) inchildren.Methods MethodsAmong 198 children with community acquired pneumonia (CAP), 56 cases were diagnosed as mycoplasmapneumonia. The epidemiology, clinical manifestation, peripheral hemogram, X-ray chest film, MP-IgM of CAP patients were retrospectively analyzed. According to the Guidelines for Management of Childhood Community Acquired Pneumonia (trial version), the patients were treated with erythromycin lactobionate or azithromycin.results ResultsThe overall incidence rate of MP was28.3%, there were no significant differences in incidence rate between seasons and age groups. The rate of chest x-ray changes of left lung in MP was 44.6% ,while that of non-MP pneumonia was 21.8% (P<0.01). The CRP in MP were higher than that in non-MP pneumonia (P<0.05). There was no difference in the changes of WBC and neutrophils count between MP and non-MP pneumonia (P >0.05). The total effective rate of macrolide antibiotics in treatment of MP was 89.3%, that of CAP was 95.8%( P > 0.05). In the treatment of MP the effective rate of erythromycin lactobionate was 89.2%, that of azithromycin was 89.5%( P >0.05). No serious side effects were observed when macrolide antibiotics were administered with slow intravenous dropping. Macrolide antibiotics (erythromycin lactobionate or azithromycin) can be used as the primary antibiotics to treat children CAP including MP.关键词
社区获得性肺炎/大环内酯类抗生素/流行病学/疗效Key words
Community acquired pneumonia(CAP)/Macrolide antibiotics Epidemiology/Curative effect引用本文复制引用
沈亚娟,王金龙,吴春红,陈桂峰..小儿支原体肺炎临床特征及大环内酯类抗生素疗效分析[J].浙江医学,2012,34(5):356-358,363,4.
