不同宫颈组织中PIK3CA、PTEN和p16蛋白表达及其与HPV16/18感染的关系OA北大核心CSCDCSTPCD
Correlation between PIK3CA,PTEN and p16 Protein Expression and Human Papillomavirus Infection in Different Cervical Tissues
目的 探讨PIK3CA、PTEN和p16蛋白在人正常宫颈上皮、宫颈上皮内瘤变(cervical intraepithelial neoplasia,CIN)和宫颈鳞癌组织中的表达,以及PIK3CA、PTEN和p16蛋白表达与人乳头瘤病毒(human papillomavirus,HPV)感染之间的关系.方法 采用免疫组织化学二步法在22例健康者官颈组织、72例宫颈上皮内瘤变(cervical intraepithelial neoplasia…查看全部>>
Objective To evaluate correlations between PIK3CA.PTEN and p16 protein expresS1on, and human papillomavirus (HPV) infection in the normal cervix epithelium, cervical intraepithelial neoplaS1a (CIN) and cervix squamous cell carcinoma (SCO. Methods The immunohistochemical staining PV-9000 method was used to detect the expresS1on of PIK3CA.PTEN and pl6 protein and high-risk HPV16/18 infection was detected by chromogenic in S1tu Hybridization in 30 cases of SCC …查看全部>>
孙军;胡俊波;陈洪雷;李蓓芸;夏和顺
430070 武汉,湖北省妇幼保健院病理科430070 武汉,湖北省妇幼保健院病理科武汉大学基础医学院病理学教研室武汉大学基础医学院病理学教研室湖北省肿瘤医院病理科
医药卫生
宫颈癌PIK3CAp16PTEN人乳头瘤病毒
Cervical cancerPIK3CAPTENp16 proteinHuman papillomavirus
《肿瘤防治研究》 2012 (2)
189-194,6
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