肿瘤防治研究2012，Vol.39Issue(2)：210-212,3.DOI:10.3971/j.issn.1000-8578.2012.02.023
阿扎司琼注射液预防芬太尼透皮贴剂所致的肿瘤患者恶心呕吐的疗效观察
Azasetron Prevents of Nausea and Vomiting Caused by Transdermal Fentanyl in Cancer Patients
赵迎超 1程晶 1张盛 1董晓荣 1黄方 1姜瑶1
作者信息
- 1. 430023 武汉,华中科技大学同济医学院附属协和医院肿瘤中心
- 折叠
摘要
Abstract
Objective To study the efficacy of Azasetron in prevention of transdermal fentanyl induced nausea and vomiting in cancer patients. Methods One hudred and forty patients with the moderate-severe cancer-related pain were randomly divided into test group(70 patients) and control group(70 patients). Transdermal fentanyl and Azasetron were given to test group in the first week and transdermal fentanyl alone to control group. The S1de effects of transdermal fentanyl,including nausea and vomiting, were observed within at least 2 weeks. Results (1)The incidence and intenS1ty of nausea and vomiting in the test group were S1gnificantly lower than those in the control group during the first week. As to the second week,there was no S1gnificant difference between two groups. (2)The patients in the control group had more severe nausea and vomiting in the first week than those in the following week with a S1gnificant difference. No S1gnificant difference was found in test group between the first and second week. ConcluS1on Azasetron could effectively prevent the nausea and vomiting caused by transdermal fentanyl in cancer patients.关键词
肿瘤/疼痛/芬太尼透皮贴(多瑞吉)/止吐Key words
Neoplasm/ Pain/ Transdermal fentanyl ( Durogesic) /Antiemesis分类
医药卫生引用本文复制引用
赵迎超,程晶,张盛,董晓荣,黄方,姜瑶..阿扎司琼注射液预防芬太尼透皮贴剂所致的肿瘤患者恶心呕吐的疗效观察[J].肿瘤防治研究,2012,39(2):210-212,3.
