飞行时间二次离子质谱在生物材料和生命科学中的应用(上)OA北大核心CSCDCSTPCD
Applications of Time-of-Flight Secondary Ion Mass Spectrometry (TOF-SIMS) in Biomaterials and Life Science (Part Ⅰ)
飞行时间二次离子质谱(TOF-SIMS)成为材料表面化学分析越来越重要的手段,随着分析仪器性能的不断提高,尤其是团簇离子源的发明和使用,使得TOF-SIMS在生物材料和生命科学研究中能够更接近常规性地被使用.它可以用来鉴定表面的生物分子,并且描述生物分子在单细胞表面和内部及组织切片上的二维分布.TOF-SIMS的主要测试功能包括表面质谱,化学成像及深度剖析3种.本综述(分上、下两篇)围绕这3项仪器功能,简单综述近20年内TOF-SIMS在生物材料…查看全部>>
Time-of-flight secondary ion mass spectrometry(TOF-SIMS)is becoming an important technique for chemical surface analysis since its instrumental performance has been improved. The discovery and application of the cluster ion beams in the past few years promote TOF-SIMS to be used almost as a routine analytical tool for identifying bio-molecules at surface and mapping their 2D distributions at the surface or in the interior of cells and on the cross-section of…查看全部>>
孙立民
上海交通大学分析测试中心,上海200240
化学化工
飞行时间二次离子质谱(TOF-SIMS)结构鉴定蛋白质吸附表面化学改性生物降解高分子
time-of-flight secondary ion mass spectrometry(TOF-SIMS) structural identificationprotein adsorptionchemical surface modification biodegradable polymer
《质谱学报》 2012 (1)
55-64,10
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