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怀牛膝中甾酮类成分的分离与鉴定

王秋红 杨柳 姜海 杨炳友 匡海学

中医药学报2012,Vol.40Issue(1):69-71,3.
中医药学报2012,Vol.40Issue(1):69-71,3.

怀牛膝中甾酮类成分的分离与鉴定

Isolation and Identification of Chemical Constituents of Phytoecdysteroids from the Root of Achyranthes bidentata BL

王秋红 1杨柳 1姜海 1杨炳友 1匡海学1

作者信息

  • 1. 黑龙江中医药大学北药基础与应用研究省部共建教育部重点实验室,黑龙江省中药及天然药物药效物质基础研究重点实验室,黑龙江哈尔滨150040
  • 折叠

摘要

Abstract

To investigate the chemical constituents that promote the proliferation of osteoblast in vitro from the root of Achyranthes bidentata BL. The chemical constituents were isolated by various isolation methods (silica gel, ODS and HPLC column chromatography) and their structures were elucidated by the analysis of spectral data ( UV, NMR and MS) . Five phytoecdysteroids compounds were obtained and elucidated as following: β - ecdysterone (1) , 25S - inokos-terone (2) , 25R - inokosterone (3) , stachysterone C (4) and stachysterone D (5). The fourth compound is reported from the plant for the first time.

关键词

怀牛膝/化学成分/甾酮类

Key words

Achyranthes bidentata BL. / Chemical Constituents/ Phytoecdysteroid

分类

医药卫生

引用本文复制引用

王秋红,杨柳,姜海,杨炳友,匡海学..怀牛膝中甾酮类成分的分离与鉴定[J].中医药学报,2012,40(1):69-71,3.

基金项目

国家自然科学基金(No.30730113) (No.30730113)

黑龙江省博士后创新基金(No.LBH-Z10020) (No.LBH-Z10020)

中医药学报

OACSTPCD

1002-2392

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