安徽医科大学学报2012，Vol.47Issue(7)：839-841,3.
血糖漂移与2型糖尿病视网膜病变发生的相关性
Associations between amplitude of glycemic excursion and retinopathy in type 2 diabetic
戴武 1曹永红 1叶军 1章容 1刘燕 1汪运生1
作者信息
- 1. 安徽医科大学附属合肥医院(合肥市第二人民医院)内分泌科,合肥,230011
- 折叠
摘要
Abstract
Objective To investigate the amplitude of glycemic excursion and its relation with retinopathy in type 2 diabetic. Methods According to the fundus photographic results, 138 cases of type 2 diabetic patients were classified to without retinopathy group ( NDR ) and diabetic retinopathy group ( DR ). Age, duration of diabetes, blood pressure ( BP ), fasting plasma glucose ( FBG ), postprandial plasma glucose ( 2hPG ), glycosylated hemoglobin ( HbA1c ),urinary albumin/creatinine ( A/C ), triglyceride ( TG ), cholesterol ( TC ), high density lipoprotein ( HDL-C ), low density lipoprotein ( LDL-C ), fasting C peptide were compared in the two groups. At the same time the two group patients were measured by continuous glucose monitoring system ( CGMS ) for 72 h, and the blood glucose fluctuation index difference were observed in the two groups. Finally using the logistic regression analysis of DR and the related factors. Results Age, course of disease, the mean blood glucose level ( MBG ), days of mean amplitude of glycemic excursions ( MAGE ) were significant difference in the two groups( P <0. 01 ). Logistic analysis results showed that duration of diabetes and MAGE was an independent risk factor of DR( P < 0. 01 ), but MBG whether or not the independent risk factor DR remained to deliberate( P =0. 05 ). Conclusion Diabetic duration, MAGE is the independent risk factors of DR. Blood glucose fluctuation may aggravate the progression of DR, so it need early interention.关键词
糖尿病视网膜病变/平均血糖漂移幅度/糖尿病病程/独立危险因素Key words
diabetic retinopathy/ mean amplitude of glycemic excursions/ duration of diabetes/ independent risk factor分类
医药卫生引用本文复制引用
戴武,曹永红,叶军,章容,刘燕,汪运生..血糖漂移与2型糖尿病视网膜病变发生的相关性[J].安徽医科大学学报,2012,47(7):839-841,3.
