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下肢动脉硬化闭塞症患者介入术后P-选择素和内皮素1的表达

江涛 余昌俊 陈智勇 余康敏 陈昌裕

安徽医科大学学报2012,Vol.47Issue(7):866-868,3.
安徽医科大学学报2012,Vol.47Issue(7):866-868,3.

下肢动脉硬化闭塞症患者介入术后P-选择素和内皮素1的表达

Expression of P-selectin, endothelin-1 in patients with peripheral arterial disease after PTA and endovascular stent

江涛 1余昌俊 1陈智勇 1余康敏 1陈昌裕1

作者信息

  • 1. 安徽医科大学第一附属医院血管外科,合肥,230022
  • 折叠

摘要

Abstract

To explore the expression and significance of plasma P-selectin( PS ) and endothelin-1 ( ET-1 ) in patients with peripheral arterial disease ( PAD ) after percutaneous transluminal angioplasty( PTA ) and endovascular stent. The levels of PS and ET-1 before PTA and endovascular stent and 1 h,6 h,24 h,2 weeks after stenting were measured in all twenty patients with PAD. The levels of PS and ET-1 increased obviously at 1 h,6 h,24 h,2 weeks after PTA and endovascular stent. The levels of PS and ET-1 were activated to some extent after PTA and endovascular stent. Monitoring these biological indexes after PTA and endovascular stent may be of great value of clinical therapy and judgment of prognosis.

关键词

P选择素/内皮素1/下肢动脉硬化性闭塞症/经皮腔内血管成形术/支架置入术

Key words

P-selectin/ endothelin-1/ peripheral arterial disease/ percutaneous transluminal angioplasty/ stent

分类

医药卫生

引用本文复制引用

江涛,余昌俊,陈智勇,余康敏,陈昌裕..下肢动脉硬化闭塞症患者介入术后P-选择素和内皮素1的表达[J].安徽医科大学学报,2012,47(7):866-868,3.

安徽医科大学学报

OA北大核心CSTPCD

1000-1492

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