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胚胎第3天形态与非整倍体的相关性研究

郝燕 周平 章志国 曹云霞

安徽医科大学学报2012,Vol.47Issue(7):868-870,3.
安徽医科大学学报2012,Vol.47Issue(7):868-870,3.

胚胎第3天形态与非整倍体的相关性研究

The relationship between Day-3 embryo morphology and aneuploid

郝燕 1周平 1章志国 1曹云霞1

作者信息

  • 1. 安徽医科大学第一附属医院生殖中心,合肥,230022
  • 折叠

摘要

Abstract

To apply two rounds of FISH in 62 embryos to screen 8 chromosomes :13, 15, 16, 18, 21, 22, X and Y, and to analyse the relationship between Day-3 embryo morphology and aneuploid. With the increasing of fragments ratio, normal chromosome embryos were decreasing. The ratio of normal chromosome embryos in 8 cells embryos group and non-8 cells group was 44. 4% and 34. 8% respectively( P > 0. 05 ). Normal chromosome embryos ratio in embryos containing even blastomeres was higher than that of uneven embryos( P <0. 05 ). Selecting embryos according to criterion morphological characteristics of chromosomes at present still has some limitations.

关键词

植入前遗传学筛查/荧光原位杂交/非整倍体

分类

医药卫生

引用本文复制引用

郝燕,周平,章志国,曹云霞..胚胎第3天形态与非整倍体的相关性研究[J].安徽医科大学学报,2012,47(7):868-870,3.

基金项目

安徽高校省级自然科学基金研究重点项目(编号:KJ2009A77) (编号:KJ2009A77)

安徽医科大学学报

OA北大核心CSTPCD

1000-1492

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