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豚草提取液对小鼠肝脏CarE活性及蛋白质含量的影响

张欣倩 张国财 包颖 赵博 张秋爽

北京林业大学学报2012,Vol.34Issue(2):109-111,3.
北京林业大学学报2012,Vol.34Issue(2):109-111,3.

豚草提取液对小鼠肝脏CarE活性及蛋白质含量的影响

Effects of Ambrosia artemisiifolia extraction on CarE activity and protein content in mice liver.

张欣倩 1张国财 1包颖 1赵博 1张秋爽1

作者信息

  • 1. 东北林业大学林学院
  • 折叠

摘要

Abstract

The activity component in Ambrosia artemisiifolia was extracted with ultrasonic method and then the mice was fed through pouring the fluid into stomach. The organophosphorus pesticide DDVP and blank treatment were taken as control. The purpose of this research was to study the extracting solution of A. artemisiifolia's effects on the activity of CarE and protein content of mammals. The results showed that extracting solution of A. artemisiifolia had the effect of activation on CarE. The enzyme activity value increased to 15. 006μmol/( min .mg) markedly during 6 hours after feeding pesticide. Then it decreased gradually and reached 9. 156μmol/(min .mg) , which was basically recovered to normal until 24 hours after feeding. Apparently, DDVP has the effect of inhibition on the activity of CarE of mice liver. The activity of CarE was in the state of inhibition after feeding pesticide and the value was lower than control and recovered slowly. Furthermore, both of extracting solution of A. artemisiifolia and DDVP have the effects of inhibition on protein content of mice liver. Therefore, as pesticide and antibacterial agent, the safety of the activity components of A. artemisiifolia is better than organophosphorus pesticide.

关键词

豚草提取液/有机磷药剂/羧酸酯酶/酶活性/蛋白质含量

Key words

extracting solution of Ambrosia artemisiifolia/organophosphate pesticide/CarE/enzymeactivity/protein content

分类

医药卫生

引用本文复制引用

张欣倩,张国财,包颖,赵博,张秋爽..豚草提取液对小鼠肝脏CarE活性及蛋白质含量的影响[J].北京林业大学学报,2012,34(2):109-111,3.

基金项目

黑龙江省科技攻关项目(GB088202)、国家林业局林业科学技术推广项目([2010]31)、东北林业大学研究生论文资助项目. ()

北京林业大学学报

OA北大核心CSCDCSTPCD

1000-1522

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