吉林大学学报（信息科学版）2012，Vol.30Issue(2)：198-202,5.
siRNA分子设计研究进展
New Progress of siRNA Molecular Design
孟庆霞 1徐宝林2
作者信息
- 1. 长春工业大学信息传播工程学院,长春130012
- 2. 吉林大学计算机科学与技术学院,长春130012
- 折叠
摘要
Abstract
To design siRNA(Short-interfering Ribonucleic Acid)molecular efficiently, and reduce off-target effects of siRNA to the greatest degree, siRNA molecular design have become a hot research field. Currently siRNA molecular design must depend on the sequence and energy features and the second structural features of target, these siRNA molecular have higher efficiency of inhibiting gene expression, RNAKRNA interference) has widely applied in the field of gene discovery and disease treatment. We summarize resent research on siRNA molecular design,and provide a reference for the study of siRNA.关键词
小干扰核糖核酸分子设计/核糖核酸干扰/基因沉默/脱靶效应Key words
short-interfering RNA (siRNA) molecular design/ RN A interference (RNAi)/gene silencing/ off-target effects分类
信息技术与安全科学引用本文复制引用
孟庆霞,徐宝林..siRNA分子设计研究进展[J].吉林大学学报（信息科学版）,2012,30(2):198-202,5.
