重庆医学2012，Vol.41Issue(15)：1511-1512,2.DOI:10.3969/j.issn.1671-8348.2012.15.024
降钙素原在危重症患者呼吸机相关性肺炎早期诊断中的价值
Clinical observation on diagnostic value of procalcitonin in critically ill patients with ventilator-associated pneumonia
代江波1
作者信息
- 1. 重庆市涪陵区人民医院ICU,408000
- 折叠
摘要
Abstract
Objective To explore the diagnostic value of procalcitonin(PCT) quantification in critically ill patients with ventilator-associated pneumonia(VAP). Methods 100 critically ill patients with mechanical ventilation in ICU of our hospital from March 2009 to June 2010 were divided into VAP group and non-VAP group. The serum PCT, white blood cell(WBC) count and morning temperature were determined before treatment in the two groups, on 7 d after mechanical ventilation in the non-VAP group and within 24 h after occurrence of inflammatory manifestations during mechanical ventilation in the VAP group. The serum PCT was detected by the semi-quantitative solid-phase immunoassay with serum PCT≥O. 5 μg/L as positive result. Results Serum PCT, WBC count and morning temperature showed no obvious difference before mechanical ventilation in both groups. But the serum PCT,WBC count and morning temperature after mechanical ventilation in the VAP group were obviously elevated than those before mechanical ventilation with statistical difference between them(P<0. 05). Conclusion Serum PCT has high sensitivity and high specificity in the diagnosis of VAP. Therefore, early monitoring serum PCT level has guidance significance in early diagnosing VAP.关键词
降钙素原/呼吸机相关性肺炎/早期诊断Key words
procalcitonin/ventilator-associated pneumonia/early diagnosis引用本文复制引用
代江波..降钙素原在危重症患者呼吸机相关性肺炎早期诊断中的价值[J].重庆医学,2012,41(15):1511-1512,2.
