重庆医学2012，Vol.41Issue(16)：1589-1590,1592,3.DOI:10.3969/j.issn.1671-8348.2012.16.010
血清HGF和CA125水平检测对子宫内膜异位症诊断价值的探讨
Study on diagnostic value of testing serum Hgf and ca125 levels in patients with endometriosis
周静 1戴星 1胡鸣1
作者信息
- 1. 南昌大学第四附属医院妇产科,330002
- 折叠
摘要
Abstract
Objective To investigate the value of hepatocyt growth factor(HGF) in the pathogenesis of endometriosis(Ems) and its clinical potential value. Methods Enzyme linked immunosorbent assay(ELISA) method was involved in determining the expression of HGF and CA125 in serum in the endometriosis group(Ems) (n = 45) and the normal control group(n = 45). Results The expressions of HGF and CA125 in the Ems group were obviously higher than those in the control group with statistical differ-ence(P<0. 05). In combined detection of HGF and CA125,the positive rate was 84% in the endometriosis group,higher than 71% and 60% in the single index test respectively, meanwhile which would be up to 100% in stage III-IV. These indicated the combination detection could improve the positive rate in endometriosis, the sensitivity dropped to 43% , whereas the specificity was up to 99% , and the positive predictive value climbed up to 100%. Conclusion The expression of HGF might be involved in the pathogenesis of endometriosis, and the combination detection of serum HGF and CA125 is conducive to increase the diagnosis accuracy of endometriosis.关键词
肝细胞生长因子/CA-125抗原/血清/子宫内膜异位症Key words
hepatocyte growth factor/CA-125 antigen/ serum/ endometriosis引用本文复制引用
周静,戴星,胡鸣..血清HGF和CA125水平检测对子宫内膜异位症诊断价值的探讨[J].重庆医学,2012,41(16):1589-1590,1592,3.
