中德临床肿瘤学杂志（英文版）2012，Vol.11Issue(7)：411-413,3.DOI:10.1007/s10330-011-0910-8
Recent achievements and acute toxicity after TP concurrent chemoradiotherapy for the advanced cervical cancer
Recent achievements and acute toxicity after TP concurrent chemoradiotherapy for the advanced cervical cancer
Qinghua Ke 1Shiqiong Zhou 1Wei Du 1Yong Lei 1Min Huang 1Fei Luo 1Jiyuan Yang1
作者信息
- 1. Department of Oncology, Jingzhou Cancer Hospital, Jingzhou 434000, China
- 折叠
摘要
Abstract
Objective: The aim of our study was to investigate the early outcome of the taxotere and cisplatin chemora-diotherapy to the advanced cervical cancer. Methods: Fifty-six cases with cervical cancer (FIGO IIb to IVa) were divided randomly into two groups in the oncology hospital of Jingzhou from September 2009 to October 2010, radiotherapy alone (28 cases) and radiation plus chemotherapy (TP) group. There was no difference of radiotherapy between the two groups, the RT + C cases who accepted TP regimen during the radiation, and DDP once weekly injection of vain, according to 20 mg/m2 and taxotere once weekly i.v. according to 35 mg/m2. These regimen were given for 4–5 weeks, and some medicine for vomit-ing was given to the RT + C cases. Two groups were received an oral medicine MA 160 mg every day during the treatment. Results: The early outcome: the complete remission rate was 64.3% and partial remission rate was 35.7% in RT + C. The complete remission rate was 32.1% and partial remission rate was 39.3% in RT. The total response rate and complete remis-sion of RT + C group was higher than that of the RT group. There was significant difference between the two groups. In RT + C group, 1-year survive rate was 100.00% (28/28); in RT group, 1-year survive rate was 85.71% (24/28). There was significant difference between the two groups (χ2 = 4.31 > 3.84, P < 0.05). Conclusion: The taxotere and cisplatin chemoradiotherapy can improve the early outcome of the advanced cervical cancer, and the adverse effect are raised, but that can be endured.关键词
cervical cancer/taxotere/cisplatin/chemoradiotherapyKey words
cervical cancer/taxotere/cisplatin/chemoradiotherapy引用本文复制引用
Qinghua Ke,Shiqiong Zhou,Wei Du,Yong Lei,Min Huang,Fei Luo,Jiyuan Yang..Recent achievements and acute toxicity after TP concurrent chemoradiotherapy for the advanced cervical cancer [J].中德临床肿瘤学杂志（英文版）,2012,11(7):411-413,3.
