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两种不同训练时程方法对海马损伤大鼠水迷宫成绩的影响

边慧 方松 缪应达 余化霖

动物学研究2012,Vol.33Issue(2):237-240,4.
动物学研究2012,Vol.33Issue(2):237-240,4.DOI:10.3724/SP.J.1141.2012.02237

两种不同训练时程方法对海马损伤大鼠水迷宫成绩的影响

Influences of two different training paradigms on spatial learning and memory performance of hippocampal injured rats

边慧 1方松 1缪应达 2余化霖3

作者信息

  • 1. 昆明医学院,云南昆明650032
  • 2. 南昌大学第一附属医院医务科,江西南昌330006
  • 3. 中国人民银行昆明市中心支行,云南昆明650223
  • 折叠

摘要

Abstract

In this study, the 5 d and 7 d training paradigms were adopted to investigate the influences of different training procedures on the performance of spatial learning and memory of the hippocampal injured rats. The results showed that during the hidden-platform acquisition training, similar spatial learning dysfunctions were indicated in those two training paradigms. Whereas, when the spatial memories have been evaluated, compared with the 5 d training groups, the rats under 7 d training procedure not only crossed the platform location less, but also preferred to spend less time in the target quadrant.

关键词

水迷宫/空间学习记忆/海马损伤

Key words

Morris water maze/ Spatial learning and memory/ Hippocampal injury

分类

医药卫生

引用本文复制引用

边慧,方松,缪应达,余化霖..两种不同训练时程方法对海马损伤大鼠水迷宫成绩的影响[J].动物学研究,2012,33(2):237-240,4.

基金项目

"973"计划 (2007CB947703) (2007CB947703)

动物学研究

OA北大核心CSCDCSTPCD

0254-5853

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