南方医科大学学报2012，Vol.32Issue(4)：534-538,5.DOI:10.3969/j.issn.1673-4254.2012.04.021
肠道原发性非霍奇金淋巴瘤85例分析
Primary intestinal non-Hodgkin's lymphoma: a retrospective study of 85 cases
摘要
Abstract
Objective To review the clinical characteristics and treatment outcomes of primary intestinal non-Hodgkin's lymphomas (P1NHL) and analyze the differences between T-cell and B-cell lymphomas.Methods The characteristics of PINHL patients treated in our hospital between January 2003 and December 2010 were reviewed for their clinical manifestations,diagnosis,endoscopic findings,treatments and outcomes.Results Eighty-five cases of PINHL meeting the Dawson's criteria were identified.The median age of the patients at the time of diagnosis was 52 years and the male: female ratio was 3.05:1; 58 cases (68.2%) had B-lineage and 27 cases (31.8%) had T-cell lineage lymphomas.Compared to those with B-cell lymphoma,patients with T-cell lymphomas showed a younger age of disease onset (32 vs 56 years,PO.01) and presented with a greater incidence of such symptoms as fever,hematochezia,diarrhea and night sweats (P<0.05); T-cell lymphoma showed more multifocal and ulcerative/ulcero-infiltrative lesions under endoscope with a longer diagnosis time (4 vs 2 months,PO.01) and a greater likeliness of misdiagnosis (16/27 vs 12/58,P0.01) and poor prognosis.Extranodal NK/T-cell lymphoma was the most common type of T-cell lymphomas.Conclusions In our cases,T-cell lymphoma appeared to be more common than B-cell lymphoma with a younger onset age,more difficult diagnosis,a greater likeliness of misdiagnosis,poorer prognosis and more extranodal NK/T-cell lymphoma.关键词
非霍奇金淋巴瘤/肠道淋巴瘤/T细胞淋巴瘤/B细胞淋巴瘤Key words
non-Hodgkin's lymphoma/intestinal lymphoma/B cell lymphoma/T cell lymphoma分类
医药卫生引用本文复制引用
冉文斌,欧阳钦..肠道原发性非霍奇金淋巴瘤85例分析[J].南方医科大学学报,2012,32(4):534-538,5.基金项目
中华医学会临床医学科研专项资金项目(07040490057) （07040490057）
