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输尿管移行细胞癌术后膀胱复发的危险因素分析

叶云林 秦自科 卞军 陈明坤 黄燕平 袁小旭 孙祥宙 戴宇平

南方医科大学学报2012,Vol.32Issue(4):557-559,3.
南方医科大学学报2012,Vol.32Issue(4):557-559,3.DOI:10.3969/j.issn.1673-4254.2012.04.026

输尿管移行细胞癌术后膀胱复发的危险因素分析

Risk factors of postoperative intravesical recurrence of transitional cell carcinoma of the ureter

叶云林 1秦自科 2卞军 3陈明坤 4黄燕平 2袁小旭 3孙祥宙 1戴宇平1

作者信息

  • 1. 中山大学附属第一医院泌尿外科,广东广州510080
  • 2. 中山大学肿瘤医院泌尿外科,广东广州510060
  • 3. 中山大学华南肿瘤学国家重点实验室,广东广州510060
  • 4. 南方医科大学附属第三医院泌尿外科,广东广州510630
  • 折叠

摘要

Abstract

Objective To define the clinicopathological risk factors of intravesical recurrence of primary transitional cell carcinoma of the ureter after surgical intervention.Methods Patients with primary carcinoma of the ureter treated between January 2000 and December 2010 were retrospectively analyzed.The intravesical recurrence-free survival rate was calculated using Kaplan-Meier method.Multivariate analysis was conducted with Cox's regression.Results A total of 104 patients were enrolled,who were followed up for a median of 46 months (13-89 months).Thirty-nine of the patients showed postoperative intravesical recurrence.Urine exfoliative cytology (P=0.000),number of tumors (P=0.006),tumor grade (P=0.039) and co-existence of bladder tumor (P=0.014) were found to independently influence the postoperative intravesical recurrence.Patients with more risk factors had poorer intravesical recurrence-free survival.Conclusions Urine exfoliative cytology,number of tumors,tumor grade and co-existence of bladder tumor are independent risk factors for postoperative intravesical recurrence of primary transitional cell carcinoma of the ureter.Close follow-up and rigorous treatment are essential for patients with high risk factors.

关键词

输尿管癌/移行细胞癌/膀胱/复发/危险因素

Key words

carcinoma of the ureter/transitional cell carcinoma/bladder/recurrence/risk factors

分类

医药卫生

引用本文复制引用

叶云林,秦自科,卞军,陈明坤,黄燕平,袁小旭,孙祥宙,戴宇平..输尿管移行细胞癌术后膀胱复发的危险因素分析[J].南方医科大学学报,2012,32(4):557-559,3.

基金项目

国家自然科学基金(81072101) (81072101)

南方医科大学学报

OA北大核心CSCDCSTPCDMEDLINE

1673-4254

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