摘要
Abstract
Objective ;To compare the efficacy and safety between photoselectiye vaporization of prostate (PVP) and transurethral resection of prostate (TURP) in treating benign prostate hyperplasia (BPH). Methods:Such datebases as Cochrane library, Med-line,Embase,CNKI,CBM,Wanfang and Weipu were searched from their establishment to Dec.2011 for collecting the randomized controlled trials ( RCTs) about PVP vs TURP for the treatment of BPH,and the references of those RCTs were also searched by hand. After study selection,assessment and data extraction conducted by two reviewers independently,meta-analyses were performed using the Rev-Man 5.0 software. Results:Five studies involving 528 patients were included. The results of meta-analyses showed that:( 1)efficacy in-dieator;the IPSS,QOL,Qmax,RUV after6 months had no significant difference between the two groups (P>0.05) ;(2)safety indica-tor:compared with TURP,PVP had longer operation time [MD =28.97,95%CI(9.72,48. 21)] .shorter catheterization time [MD = -2.86,95%CI(4.58,-1.13)] .shorter hospital stay [ MD =-2. 32,95% CI(-2.79,-1. 85) ],and less blood transfusion [OR=0.08, 95%CI(0.02,0. 34)]. However,there was no significant difference in urethral stricture [OR =0.74,95%CI(0.27,2.07) ]. Conclusions :Current evidences indicate that PVP is similar to TURP in the treating effect,but it haa shorter catheterization time,hospital stay and less blood transfusion. There was no significant difference in urethral stricture.
关键词
前列腺增生/经尿道前列腺电切术/前列腺选择性绿激光汽化术/Meta分析Key words
Prostatic hyperplasia/Transurethral resection of prostate/Photoselective vaporization of prostate/Meta-analysis
分类
医药卫生