分析化学2012，Vol.40Issue(4)：551-555,5.DOI:10.3724/SP.J.1096.2012.10963
微电极阵列芯片的脂质体电融合研究
Study of Liposome Electrofusion on Microelectrode Array Chip
摘要
Abstract
Large liposomes that electrofused on a microelectrode array based microchip were prepared by using soybean lecithin and the co-evaporating method. In the electrofusion process, liposomes were aligned by the dielectrophoretic force, electroporated by using high-strength electric pulses, and subsequently fused by using continuous dielectrophoretic force. Experimental results showed that 20% liposomes could be fused on the chip, and the glass substrate and low depth-width ratio channel were helpful for the observation and control of the liposome fusion.关键词
微流控/脂质体/介电电泳/电融合/微电极Key words
Microfluidics/Liposome/Dielectrophoresis/Electrofusion/Microelectrode引用本文复制引用
蒋凤,杨军,王振宇,胡宁,郑小林,谢琳,杨忠,陈洁..微电极阵列芯片的脂质体电融合研究[J].分析化学,2012,40(4):551-555,5.基金项目
本文系国家自然科学基金(No.81071278),教育部“新世纪优秀人才支持计划”(No.NCET-09-0842),重庆市科技计划(No.CSTC2009AB5081)和重庆大学研究生创新团队建设(No.200909A1002)资助项目 （No.81071278）
