高等学校化学学报2012，Vol.33Issue(6)：1172-1176,5.DOI:10.3969/j.issn.0251-0790.2012.06.010
黄酮类药物与氯金酸的作用及其分析应用
Redox of Flavonoids with Chlorauric Acid and Its Analytical Application
摘要
Abstract
Four flavonoids including genistein, luteolin, daidzein and naringenin can reduce HAuCl4 to form gold nanoparticles in different acidity. There are good linear correlations between the signal of plasmon resonance absorption of gold nanoparticles and the concentration of four flavonoids. Thus, we developed a method to detect these four flavonoids respectively. By analyzing the molecular structure and calculating the electron cloud density distribution of the atoms using Materials-studio 4. 0, we found that suitable pH for the reaction of different flavonoids and HAuCl4 was related to the number of phenolic hydroxyl group of flavonoid and electron cloud density distribution of alkaline oxygen atoms.关键词
染料木素/木犀草素/大豆素/柚皮素/金纳米颗粒/等离子体共振吸收Key words
Genistein/Luteolin/Daidzein/Naringenin/Gold nanoparticles/Plasmon resonance absorption分类
化学化工引用本文复制引用
王慧娟,李春梅,刘跃,李原芳..黄酮类药物与氯金酸的作用及其分析应用[J].高等学校化学学报,2012,33(6):1172-1176,5.基金项目
国家"重大新药创制"科技重大专项(批准号:2010ZX09401-306-1-4)、国家自然科学基金(批准号:21175109)和重庆市自然科学基金(批准号:2010AA5015)资助. （批准号:2010ZX09401-306-1-4）
