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肝脏储备功能相关系统对肝硬化失代偿期预后的评估与分析

区映研 李晓霞 曾文铤 梁建新

国际医药卫生导报2012,Vol.18Issue(3):333-337,5.
国际医药卫生导报2012,Vol.18Issue(3):333-337,5.DOI:10.3760/cma.j.issn.1007-1245.2012.03.014

肝脏储备功能相关系统对肝硬化失代偿期预后的评估与分析

Liver reserve function for assessing and analyzing prognosis of decompensated hepatocirrhosis

区映研 1李晓霞 2曾文铤 1梁建新1

作者信息

  • 1. 广州,广州医学院第一附属医院感染内科
  • 2. 广州,广州医学院第一附属医院内科
  • 折叠

摘要

Abstract

Objective To retrospectively analyze the short-term survival status of decompensated hepatocirrhosis by the Model for End-Stage Liver Disease ( MELD ) and Child-Turcotte-Pugh ( CTP ) score and to predict 3-month and one-year mortality rates in decompensated hepatocirrhosis.Methods MELD,MELD-Na,and CTP score decompensated hepatocirrhosis were used to classify and graded decompensated hepatocirrhosis in 119 patients.The 3-month and one-year morality rates were compared among patients with different MELD scores ( ≤9,10-19,20-29,and ≥30 ) or different CTP classification ( A,B,and C ).The clinical features were analyzed in the patienes during a 3-month and a one-year follow-up.Results The 3-month mortality rate was 2.17 % for MELD ≤9,10.71% for 10-19,64.29 % for 20-29,and 100 % for ≥30; and the one-year mortality was 26.09%,32.14%,57.14 %,and 100 %,respectively.The short-term mortality was associated with MELD scores.If R > 18 was used as a standard,the 3-month and one-year mortality rates were significantly higher in the group with R > 18 than in the group with R=18 ( P< 0.01 for both comparisons ).The 3-month mortality rate was 6.78 % for CTP A,15.38 % for B,and 42.86 % for C ( P< 0.01 ):and the one-year mortality was 11.86 %,38.46 %,and 90.48 %,respectively ( P< 0.05 ).MELD-Na was related to the short-term mortality ( 3 months and 1 year ) in decompenated hepatocirrosis ( P < 0.01 ).Conclusions Both MELD and CTP scores can accurately predict the short-term prognosis in patients with decompensated hepatocirrhosis.

关键词

肝硬化/终末期肝病模型(MELD)/Child-Turcotte-Pugh(CTP)分级

Key words

Hepatocirrhosis/Model for End-Stage Liver Disease/Child-Turcotte-Pugh score

引用本文复制引用

区映研,李晓霞,曾文铤,梁建新..肝脏储备功能相关系统对肝硬化失代偿期预后的评估与分析[J].国际医药卫生导报,2012,18(3):333-337,5.

国际医药卫生导报

1007-1245

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