国际医药卫生导报2012，Vol.18Issue(6)：846-849,4.DOI:10.3760/cma.j.issn.1007-1245.2012.06.042
高分子量角蛋白,CK19及TPO联合检测在鉴别甲状腺乳头状癌与乳头状增生中的意义
Differential diagnostic usefulness of 34 β E12, CK19 and TP0 in papillary thyroid carcinoma and papillary thyroid hyperplasia
江鹤灵 1胡名娟 1李国伟1
作者信息
- 1. 510800 广州市花都区人民医院病理科
- 折叠
摘要
Abstract
Abstract To study the application value and significance of 34E12,cytokeratin 19 (CK19)and thyroper oxidase(TP0) in the differential diagnosis between papillary thyroid carcinomas and benign thyroid papillary hyperplasia.Methods The expression of 34 β E12,CK19 and TPO protein in 38 cases of papillary thyroid carcinomas,15 cases of thyroid nodular goiter with papillary hyperplasia and 15 cases of adenomas with papillary hyperplasia were detected by immunohistochemistry method.Results The positive rats of 34 β E12,CK19 and TP0 in papillary thyroid carcinomas and hyperplasia disease of thyroid were 89.5％ and 3.3％ (P＜ 0.01); 84.2％ and 16.7％ (P＜ 0.01); 10.5％ and 96.7％ (P＜ 0.01).Conclusion 34 β E12, CK19 and TP0 expressions are useful in differential diagnosis for papillary thyroid carcinoma and benign papillary thyroid hyperplasia.关键词
甲状腺乳头状癌/高分子量角蛋白(34 β E12)/CK19/TP0/免疫组化Key words
Papillary thyroid carcinoma/High molecular weight cytokeratin(34 β E 12 )/Cytokeratin 19(CK19)/Thyroperoxidase(TP0)/Immunohistochemistry引用本文复制引用
江鹤灵,胡名娟,李国伟..高分子量角蛋白,CK19及TPO联合检测在鉴别甲状腺乳头状癌与乳头状增生中的意义[J].国际医药卫生导报,2012,18(6):846-849,4.
