国际医药卫生导报2012，Vol.18Issue(6)：852-855,4.DOI:10.3760/cma.j.issn.1007-1245.2012.06.044
两面针中氯化两面针碱提取工艺优化
Optimization of extract conditions of nitidine chloride
谭伯森 1马永良 2周晓平 1范艳冰3
作者信息
- 1. 510170 广州,广州医学院荔湾医院
- 2. 510120 广州,中山大学孙逸仙纪念医院
- 3. 510140 广州,广州医学院羊城医院
- 折叠
摘要
Abstract
Objective To explore the effects of different pH levels in extracting conditions of nitidine chloride.Methods Zanthoxylum nitidum(Roxb.)Dc.was extracted as experimental material,the extract conditions of Nitidine chloride was optimized by orthogonal experiment; the extraction rate by the content of Nitidine chloride was determined by high performance liquid chromatography (HPLC).Results The best extract conditions of Nitidine chloride was adding 10 times of appropriate level and 40 ℃ water,and the acidity of the solution was adjusted to pH=1.0.Conclusion The optimum extract conditions is appropriate for industry production.关键词
氯化两面针碱/两面针/提取/pHKey words
Nitidine chloride/Zanthoxylum nitidum(Roxb.)Dc./Extract/pH引用本文复制引用
谭伯森,马永良,周晓平,范艳冰..两面针中氯化两面针碱提取工艺优化[J].国际医药卫生导报,2012,18(6):852-855,4.
