国际医药卫生导报2012,Vol.18Issue(8):1136-1138,3.DOI:10.3760/cma.j.issn.1007-1245.2012.08.030
克拉霉素联合甲硝唑及叶酸治疗49例萎缩性胃炎的临床效果分析
Clinical efficacy analysis on clarithromycin combined with metronidazole and folic acid in treatment for 49 cases of chronic atrophic gastritis
饶进 1陈福生 1柳胜奇2
作者信息
- 1. 523843 东莞市长安医院
- 2. 523320 东莞,石龙博爱医院
- 折叠
摘要
Abstract
Objectives To explore and analyze the clinical effects of clarithromycin combined with metronidazole and folic acid in treatment for 49 cases of chronic atrophic gastritis.Methods 98 cases of chronic atrophic gastritis received from March 2009 to March 2010 were randomly divided into two groups:control group and treatment group,49 cases for each group.The control group was given clarithromycin and metronidazole for treatment,and the treatment group used clarithromycin combined with metronidazole and folic acid.The clinical effect after treatment was compared in these two groups.Results As for the 49 cases of treatment group,26 cases were significantly effective,22 cases were effectual and 1 case was withont effect,with a total effective rate of 97.96%; as for the control group,there were 15 significant effective cases,29 cases effectual,and 5 with no effect respectively,and the total effective rate was 89.80%.There was statistical significant difference between the two groups (x2=6.58,P<0.05).5 cases in treatment group had adverse effects,accounting for 10.20%,while 4 cases in control group had adverse effect,taking up 8.16%.There was no significant difference in incidence between the two groups (P>0.05).Conclusions The therapy of clarithromycin combined with metronidazole and folic acid has great effect in curing chronic atrophic gastritis,with less adverse effects and worthy of clinical application.关键词
克拉霉素/甲硝唑/叶酸/萎缩性胃炎Key words
Clarithromycin/Metronidazole/Folic Acid/Chronic atrophic gastritis引用本文复制引用
饶进,陈福生,柳胜奇..克拉霉素联合甲硝唑及叶酸治疗49例萎缩性胃炎的临床效果分析[J].国际医药卫生导报,2012,18(8):1136-1138,3.