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NT-proBNP和cTnI联合检测对慢性心力衰竭患者诊断和预后评估价值

王涵 梁服泉 张杰灵 周建球 罗林佳

国际医药卫生导报2012,Vol.18Issue(8):1170-1172,3.
国际医药卫生导报2012,Vol.18Issue(8):1170-1172,3.DOI:10.3760/cma.j.issn.1007-1245.2012.08.045

NT-proBNP和cTnI联合检测对慢性心力衰竭患者诊断和预后评估价值

Diagnosis and prognosia value of combined detection of NT-proBNP and cTnI on patients with chronic heart failure

王涵 1梁服泉 1张杰灵 1周建球 1罗林佳2

作者信息

  • 1. 519070 珠海市香洲区人民医院检验科
  • 2. 519070 珠海市香洲区人民医院内科
  • 折叠

摘要

Abstract

Objective To explore the diagnosis and prognosis value of combined detection of NT-proBNP and cTnI on patients with chronic heart failure.Methods 120 patients with chronic heart failure in our hospital from June 2009 to June 2011 were studied:the plasma NT-proBNP and cTnI levels at different NYHA class; the cardiovascular events of different NT-proBNP and cTnI levels during follow up.Results The NT-proBNP and cTnI levels of heart failure patients were (1664.8 ± 632.9) pg/ml and (0.35 ± 0.12) ng/ml,while the NT-proBNP and cTnI levels of healthy subjects were (92.3 ± 6.7) pg/ml and (0.01 ± 0.03) ng/ml.Two indicators of heart failure patients were higher than those of healthy subjects (P< 0.01),which also increased in accordance with the severity of heart failure.The cardiovascular events of patients with low levels of NT-proBNP and cTnI were 17.9% and 19.5% separately,while the events of high level were 43.4% and 50.0%.Conclusions NT-proBNP and cTnI can be used for the diagnosis and prognosis of chronic heart failure.More attention should be paid to those with high plasma NT-proBNP and cTnI level,which was worth being promoted clinically.

关键词

NT-proBNP/cTnI/慢性心力衰竭/诊断和预后评估

Key words

NT-proBNP/cTnI/Chronic heart failure/Diagnosis and prognosis

引用本文复制引用

王涵,梁服泉,张杰灵,周建球,罗林佳..NT-proBNP和cTnI联合检测对慢性心力衰竭患者诊断和预后评估价值[J].国际医药卫生导报,2012,18(8):1170-1172,3.

国际医药卫生导报

1007-1245

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