广东药学院学报2012，Vol.28Issue(1)：51-53,3.DOI:10.3969/j.issn.1006-8783.2012.01.014
吸附伏安法测定药品中对乙酰氨基酚的含量
Adsorptive voltammetric determination of paracetamol in drugs
温金莲 1周清 1龙宁 1朱明芳1
作者信息
- 1. 广东药学院药科学院,广东广州510006
- 折叠
摘要
Abstract
Objective To establish the determination method of paracetamol in drugs by carbon paste electrode anodic adsorptive voltammetry. Methods The electrode was prepared by carbon powder and liquid paraffin(4: 1) ,in a hydrochloric acid solution(pH =0. 50). Paracetamol shows a sensitive adsorptive oxidation peak at 0.706 V (reference electrode:Ag-AgCl). Results The linearity was good between 3. 13 × 10-6 -2.0 × 10-4 mol · L-1 with correlation coefficient of 0.999 5. The detection limit was 6.6 ×10-8 mol · L-1. This method was applied with satisfactory results. Conclusion The method is simple,rapid and accurate,which can be used for the quality control of paracetamol related drugs.关键词
对乙酰氨基酚/吸附伏安法/碳糊电极/对乙酰氨基酚片/氨咖黄敏胶囊Key words
paracetamol/adsorptive voltammetry/carbon paste electrodes/paracetamol tablet/ankahuangmin capsule分类
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温金莲,周清,龙宁,朱明芳..吸附伏安法测定药品中对乙酰氨基酚的含量[J].广东药学院学报,2012,28(1):51-53,3.
