摘要
Abstract
Objective To analyze the clinical and endocrine metabolism features of adolescence polycystic ovary syndrome ( PCOS ), so as to seek basis for early diagnosis. Methods Sixty cases of adolescence PCOS were selected. The general information was recorded, and hirsutism and acne were observed and scored. The blood samples were taken to detect the serum hormone levels, OGTT and IRT. The volume of ovary and the number of follicles were measured through intrarectal sonography. Results 100% of the adolescence PCOS suffered abnormal menstruation, 83. 3% of them had polycystic ovaries( PCO ), 53. 3% of them had central obesity, and 45. 0% of them had obesity including 81.5% accompanying with IR. Compared with patients with non-obesity, the age, BMI, WHR, OGTT2h and insulin levels at each time point were significantly different ( t = 2. 38 ~7. 36, all P <0.05 ). There were 68. 3% patients with IR, and their age, BMI, WHR, testosterone, serum glucose and insulin level at each time point were significantly different compared with patients with NIR ( t = 2. 14 ~ 5. 06, all P < 0. 05 ). There were 85. 0% of patients with hyperandrogenism. Compared with non-hyperandrogenism ones, there was significant difference in testosteone level ( t = 5. 45, P < 0. 05 ). Conclusion Most of adolescence PCOS accompany with menstrual disorders, PCO, central obesity, IR and hyperandrogenism. Menstrual disorder mainly embodies on oligomenorrhea, followed by secondary amenorrhea. Obese adolescence PCOS has a remarkable trend of suffering IR.关键词
青春期/多囊卵巢综合征/临床特征/内分泌代谢特征Key words
adolescence/ polycystic ovary syndrome ( PCOS )/ clinical features/ endocrine metabolism features分类
医药卫生
