表皮生长因子受体与肺泡上皮不典型腺瘤样增生的关系OACSTPCD
Epidermal growth factor receptor and alveolar epithelial atypical adenomatous hyperplasia
肺癌是人类常见的恶性肿瘤,肺腺癌是其主要类型之一.细支气管肺泡癌(bronchioloalveolar lung carcinoma,BAC)是肺腺癌的一个特殊类型.肺泡上皮不典型腺瘤样增生(atypical adenomatous hyperplasia,AAH)可能是BAC或腺癌的癌前病变,甚至是其早期癌.表皮生长因子受体(epidermal growth factor receptor,EGFR)的过表达和(或)突变与肺癌尤其是非小细胞肺癌…查看全部>>
Lung cancer is a common malignant tumor and lung adenocarcinoma is the main type of it. Bronchioloalveolar lung carcinoma (BAC) is a special type of lung adenocarcinoma. Research indicates that alveolar epithelial atypical adenomatous hyperplasia (AAH) in BAC or adenocarcinoma may be a precancerous lesion, even in the early stage of cancer. Overexpression and/or mutatioin of epidermal growth factor receptor (EGFR) is closely related to the occurrence, develo…查看全部>>
黄谦
中南大学湘雅二医院病理科,长沙410011;岳阳职业技术学院医学基础部,湖南岳阳414000
肺癌肺泡上皮不典型腺瘤样增生表皮生长因子受体细支气管肺泡癌突变
lung cancer atypical adenomatous hyperplasia epidermal growth factor receptor bronchioloalveolar lung carcinoma mutation
《国际病理科学与临床杂志》 2012 (1)
84-87,4
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