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微创颅内血肿清除术对高血压性脑出血患者血肿周围水肿及血清炎性因子的影响

宛丰 吕衍文

神经损伤与功能重建2012,Vol.7Issue(3):195-197,3.
神经损伤与功能重建2012,Vol.7Issue(3):195-197,3.DOI:10.3870/sjsscj.2012.03.011

微创颅内血肿清除术对高血压性脑出血患者血肿周围水肿及血清炎性因子的影响

Effect of Minimally Invasive Hematoma on Edema around Hematoma and Serum Levels of Inflammatory Cytokines in Patients with Hypertensive Intracerebral Hemorrhage

宛丰 1吕衍文1

作者信息

  • 1. 黄冈市中心医院神经内科,湖北,黄冈,438000
  • 折叠

摘要

Abstract

Objective: To investigate the effects of minimally invasive hematoma on edema around hematoma and serum levels of inflammatory cytokines in patients with hypertensive in-tracerebral hemorrhage. Methods: Sixty-nine patients with acute ICH and hypertension were randomly divided into minimally invasive group and control group. All patients were given conventional treatment. In the minimally invasive group, the patients were treated with minimally invasive hematoma removal evacuation in addition to conventional therapy. Before treatment and days 7 and 14 after treatment, serum hs-CRP, IL-6, TNF-oc contents in kk the patients in the two groups were tested. Meanwhile, the brain hematoma and edema around hematoma volume were measured through CT. Results: At days 7 14 after treatment, the serum hs-CRP, IL-6, and TNF-oc content and the edema around hematoma volume in the minimally invasive group were significantly lower than those in the control group. The neurological function deficit score in the minimally invasive group was significantly lower than that in control group. Conclusion: Minimally invasive hematoma evacuation could reduce hs-CRP, IL-6, and TNF-oc levels and the edema around hematoma, thus improve the outcomes of cerebral hemorrhage.

关键词

高血压性脑出血/微创颅内血肿清除术/血肿周围水肿/超敏C反应蛋白/白介素-6/肿瘤坏死因子-α

Key words

hypertensive intracerebral hemorrhage/ minimally invasive hematoma/ edema/ high-sensitivity C-reactive protein/ interleukin-6 / tumor necrosis factor-ct

分类

医药卫生

引用本文复制引用

宛丰,吕衍文..微创颅内血肿清除术对高血压性脑出血患者血肿周围水肿及血清炎性因子的影响[J].神经损伤与功能重建,2012,7(3):195-197,3.

神经损伤与功能重建

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