南方农业学报2012，Vol.43Issue(2)：249-252,4.DOI:10.3969/j:issn.2095-1191.2012.02.249
猪流感病毒H1N2亚型油乳剂灭活苗的免疫效果
Immunization effect of inactivated oil-emulsion vaccine on pigs infected with H1N2 subtype swine influenza virus
摘要
Abstract
[Objective] The effect of inactivated oil-emulsion vaccine for swine influenza virus (SIV) H1N2 subtype was evaluated in order to prevent the occurrence and spread of SIV efficiently. [ Method ]The immunized pigs were injected intramuscularly with different doses (2,4 and 6 mL per pig) of inactivated H1N2 virus, and the blood of pigs were collected and the titer of antibody was tested by HI assay for 10 successive weeks. The clinical symptoms were investigated and virus detection tests were performed. [Result]The results showed antibody titers of pigs immunized with moderate dose (4 mL per pig) and high dose (6 mL per pig) were higher than that of the low dose (2 mL per pig). The body temperatures of pigs between immunized group and control group displayed no significant differences. Pigs of the immunized group had no obvious clinical symptoms, indicating that pigs were well protected by vaccine. [ Conclusion ] Inactivated oil-emulsion vaccine of SIV H1N2 subtype owns good immune property and protective effect against the attack of similar subtype virus, its best injection dose is 4 mL per pig.关键词
猪流感病毒/H1N2亚型/油乳剂灭活苗/免疫/攻毒Key words
swine influenza virus/ H1N2 subtype/ inactivated oil-emulsion vaccine/ immunity/ infection分类
农业科技引用本文复制引用
陆增荣,刘磊,赵武,陈泽祥,张民秀,黄伟坚,侯韶毅,卢桂娟,肖雄,黄福标,卢冰霞,郭旋..猪流感病毒H1N2亚型油乳剂灭活苗的免疫效果[J].南方农业学报,2012,43(2):249-252,4.基金项目
广西科学研究与技术开发计划项目(桂科攻10100014-4) （桂科攻10100014-4）
