华东理工大学学报：自然科学版2012，Vol.38Issue(1)：39-44,6.
用数学方法设计固定化产腈水解酶细胞填充床反应器的关键操作参数
Design of Key Operational Parameters of Immobilized Nitrilase-Producing Cells Packed-Bed Reactor by Methimatical Method
摘要
Abstract
By constructing an empirical equation with algebraic form,the key operational parameters of immobilized nitrilase-producing cells packed-bed reactor were determined successfully for nicotinic acid production.A simplified equation,L=7.898u cS0＋114.6u＋0.028,which describes the relationship of the three key operational parameters（column length L,flow rate u and substrate concentration cS0）,was obtained by analyzing the numerical solutions of the established axial dispersion model（one-dimension） of packed-bed reactor.Under the condition of 3-cyanopyridine conversion rate of 95% and the void fraction of 0.11,the optimal operational parameters of packed-bed reactor were obtained by computation based on the algebraic equation for the purpose of maximization of the nicotinic acid production.关键词
填充床反应器/轴向扩散模型/关键操作参数/代数方程/尼克酸Key words
packed-bed reactor/axial dispersion model/key operational parameters/algebraic equation/nicotinic acid分类
生物学引用本文复制引用
杨春生,王学东,魏东芝..用数学方法设计固定化产腈水解酶细胞填充床反应器的关键操作参数[J].华东理工大学学报：自然科学版,2012,38(1):39-44,6.基金项目
国家重点基础研究发展（973）计划 （）
