郑州大学学报（医学版）2012，Vol.47Issue(3)：284-286,3.DOI:10.3969/j.issn.1671-6825.2012.03.002
河南省青年食管癌家族史及环境和行为影响因素
Impact of family history,smoking,drinking and environmental factors on esophageal cancer in young patients from Henan
摘要
Abstract
Aim:To analyze the pathogenic factors associated with esophageal carcinoma in young people(≤40 years)in Henan province.Methods:Applying the questionnaire survey to compare the difference between gender, family history, high-low incidence area, body mass index(BMI),smoking, and alcoholic drinking in 1 405 young people with esophageal carcinoma and 2 445 young healthy people,so as to analyze the dangerous factors of the esophageal cancer.Results:Incidence of esophageal carcinoma in men was higher than that in women,positive family history (OR=25.616,95%CI=20.431～32.117) was are the major dangerous factor of the esophageal cancer, the second and third were high incidence area(OR=6.440,95%CI=4.791～8.655) and BMI<18.5 kg/m2(OR=5.656,95%CI=1.433～22.319), while BMI>24 kg/m2 reduced the risk of esophageal carcinoma in young adults.Conclusion:Young men with positive family history in high incidence area in Henan province are inclined to develop esophageal carcinoma.关键词
食管癌/青年人/家族史/吸烟/喝酒Key words
esophageal carcinoma/young adults/family history/smoking/drinking分类
医药卫生引用本文复制引用
袁艺,李兴川,路勤,原园,逯越,王立东..河南省青年食管癌家族史及环境和行为影响因素[J].郑州大学学报（医学版）,2012,47(3):284-286,3.基金项目
国家杰出青年科学基金资助项目 30025016 （）
国家自然科学基金资助项目 30670956 （）
河南省高校创新人才工程基金资助项目 1999125 （）
河南省医学创新人才工程基金资助项目 200084 （）
