中医学报2012，Vol.27Issue(6)：750-752,3.
参松养心胶囊对阵发性心房颤动患者P波离散度及高敏C-反应蛋白和白细胞介素-6的影响
Effect of Shensong Yangxin Capsule on P-wave Dispersion Degree,High Sensitivity C-Reactive Protein and Interleukin-6 in Patients with Paroxysmal Atrial Fibrillation
摘要
Abstract
Objective:To discuss the effect of Shensong Yangxin Capsule on p-wave dispersion degree,high sensitivity c-reactive protein and lnlerleukin-6 in patients with paroxysmal atrial fibrillation. Methods;76 patients were divided into three groups,the control group, the Shensong Yangxin group,the routine treatment group.30 cases of sinus rhythmia patients (including 21 cases of primary hypertension patients and 9 cases of CHD patients) were in the control group, and treated with conventional drugs in cardiology department (ARB.CCB and uretic drugs were used for hypertension patients;(3-receptor retardant,Stations and nitrate drugs were used for CHD patients). The other 46 cases of paroxysmal atrial fibrillation were randomly divided into the routine treatment group and the Shensong Yangxin Group with each of 23 patients. The routine treatment group only treated primary disease (ARB, CCB and uretic drugs were used in hypertension patients according to their disease conditions; p-receptor retardant, Stations and nitrate drugs were used in CHD patients according to their disease conditions). Shensong Yangxin Croup was mainly treated by Shensong Yangxin Capsule (produced by Yiling Pharmaceutical Limited Company in Hebei Province,4 Capsules once,3 times per day). Levels of Pd,hs-CRP and IL-6 were determined before the treatment and 3 months after the treatment, then the relationship between them and atrial fibrillation was analyzed. Results: Before the treatment, levels of Pd, hsCRP and IL-6 in the routine treatment group and the Shensong Yangxin group were obviously higher than the control group(/'<0.05). After the treatment,levels of Pd.hsCRP and IL-6 in the routine treatment group had no ohvious changes compared with the baseline level before treatment(P>0.05) ,but levels of Pd,hsCRP and IL-6 in Shensong Yangxin group were much lower than the level before treatment (P < 0. 05 ). Conclusion: Shensong Yangxin Capsulf can decrease the P-wave dispersion degree of paroxysmal atrial fibrillation patients, reduce the increased hs-CRP and IL-6 level, which has certain preventive and curative effects on the recurrence of paroxysmal atrial fibrillation.关键词
参松养心胶囊/阵发性房颤/窦性心律/高血压/冠状动脉性心脏病/P波离散度/C-反应蛋白/白细胞介素-6Key words
shensong yangxin capsule/ paroxysmal atrial fibrillation/ sinus rhythmia {hypertension/ coronary artery heart disease/ P-wave dispersion degree/ C-reactive protein/ Interleukin-6分类
医药卫生引用本文复制引用
刘新灿,陈晓玲,张正勋,朱明军,朱翠玲..参松养心胶囊对阵发性心房颤动患者P波离散度及高敏C-反应蛋白和白细胞介素-6的影响[J].中医学报,2012,27(6):750-752,3.基金项目
河南省教育厅自然科学基金(编号:200820148) （编号:200820148）
